Question: Why has it been difficult to make a vaccine for HIV yet it took a short time to make one for COVID-19?

Brayan Odeka answered on 18 Aug 2025:

mmhhh, am tempted to tell you what i really think about this…,even presidents and top leaders,including kenyan doctors still ask themselves how possible this was. HIV mutates too fast, hides inside human DNA, and destroys the immune system itself, making vaccine design extremely hard.

COVID-19, by comparison, was more predictable, had existing research, and could be targeted with new vaccine technology. Scientists already had decades of research on coronaviruses (SARS in 2003, MERS in 2012).

mRNA vaccine technology was ready and waiting for a test case. COVID-19 became the chance to apply it.

COVID-19 mutates, but much slower than HIV. That made it possible to create effective vaccines within a year.

but……your curiosity can be as well make sense, maybe some people knew exactly what was coming,planned and prepared for it,oooh, dont worry about this