• Question: Can two disease that are revealed by genetically modified sheep that produce medicinal protein in milk heamophilia emphysema

    Asked by Jackson mwangemi on 15 Jul 2025.
    • Photo: DORCAS CHEBET

      DORCAS CHEBET answered on 15 Jul 2025:


      Yes, genetically modified sheep have been used to produce medicinal proteins in their milk that help treat diseases such as haemophilia and emphysema; for haemophilia, the sheep produce clotting factors needed to stop bleeding, and for emphysema, they produce alpha-1 antitrypsin, a protein that protects the lungs from damage.

    • Photo: Justa Mwangi

      Justa Mwangi answered on 16 Jul 2025:


      Genetically modified sheep have been developed to produce medicinal proteins in their milk for treating certain diseases. Two diseases targeted by this technology are:

      Hemophilia: Genetically engineered sheep, like Polly, were created to produce human coagulation factor IX (FIX) in their milk. FIX is a blood-clotting protein deficient in individuals with hemophilia B, also known as Christmas disease.
      Emphysema: Transgenic sheep, such as Tracy, were engineered to produce alpha-1 antitrypsin (AAT) in their milk. AAT is a protein used to treat hereditary emphysema and cystic fibrosis caused by a deficiency in this protein.

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