Question: Explain how sickle cell anemia come to arise

Justa Mwangi answered on 16 Jul 2025:

Sickle cell anemia arises from inheriting two copies of a mutated hemoglobin gene (one from each parent), leading to the production of abnormal hemoglobin (HbS) and sickle-shaped red blood cells. These abnormal cells can block blood flow, causing various health problems. If only one copy of the mutated gene is inherited, individuals have sickle cell trait, generally not experiencing symptoms but potentially passing the gene to their children.